学年

教科

質問の種類

化学 大学生・専門学校生・社会人

緊急です、!!!! この反応機構を矢印付きでお願いしたいです、、🥺

21:21 三 46 について | セクション 2.2 NeuroPコアの不斉合成 これ 林ピロリジン触媒存在下での9aの8への有機触媒マイケ ル付加反応とそれに続くアルデヒドの還元は、我々の以 前の報告 [26]と同様に行われ、2段階で89%の収率でアル コール7aが3:1のシン/アンチジアステレオマー混合物と して得られ、シン-7aで86%のee、 アンチ-7aで90%のee であった(図3)。 続いて、 キャンディらの条件下での 酸化Nef反応により、 87%という非常に良好な収率と16:1 のジアステレオマー比で二置換ラクトン11が得られ、 はDBU触媒による熱力学的平衡によってさらに濃縮され た。ラクトンをDIBAL-Hで還元してラクトール6aを得た 後、最初のウィッティヒ反応で開環し、アルコール12を 76%の収率で得た。塩基促進脱離副生成物13の生成を抑 制するために、徹底的な最適化が必要であったことを強 調しておくべきである。 最適化された拡張性と再現性を 備えた条件は、0℃でトルエン中の過剰量のメチル(トリ フェニルホスホニウム) 臭化物から生成したイリドの懸濁 液に6aをゆっくりと制御添加し、その後室温まで昇温す るというものである(詳細は補足情報の表S1およびS2を 参照)。 8 1.A (5mol.%), NO2 P-Nitrophenol (10 mol. %) THF, 15°C, 4 days 2. NaBH4, MeOH, 0 °C, 1 h 89% (two steps), syn/anti 3:1 OPMB 9a *NO2 + HO. HO. OPMB syn-7a anti-7a 86% ee NO2 OPMB 90% ee MePPh3Br, KHMDS Toluene 20°C to rt, 16 h NaNO2 AcOH DMF, 40°C, 16h 1.DBU (20mol.%.) HO THF, r.t., 16 h 2. DIBAL-H Toluene, 87%, trans/cis 16:1 OPMB OPMB 11 -78 to -50°C, 30 min 6a 97% (two steps) HO. HO -OPMB 12 76% スキーム3 13 9% OPMB A Ph Ph OTMS

未解決 回答数: 0
TOEIC・英語 大学生・専門学校生・社会人

この長文問題の答えと解説をお願いします。

15 語数: 398 語 出題校 法政大 5 We are already aware that our every move online is tracked and analyzed. But you 2-53 couldn't have known how much Facebook can learn about you from the smallest of social interactions - a 'like'*. (1) Researchers from the University of Cambridge designed (2) a simple machine-learning 2-54 system to predict Facebook users' personal information based solely on which pages they had liked. E "We were completely surprised by the accuracy of the predictions," says Michael 2-55 Kosinski, lead researcher of the project. Kosinski and colleagues built the system by scanning likes for a sample of 58,000 volunteers, and matching them up with other 10 profile details such as age, gender, and relationship status. They also matched up those likes with the results of personality and intelligence tests the volunteers had taken. The team then used their model to make predictions about other volunteers, based solely on their likes. The system can distinguish between the profiles of black and white Facebook users, 15 getting it right 95 percent of the time. It was also 90 percent accurate in separating males and females, Democrats and Republicans. Personality traits like openness and intelligence were also estimated based on likes, and were as accurate in some areas as a standard personality test designed for the task. Mixing what a user likes with many kinds of other data from their real-life activities could improve these predictions even more. 20 Voting records, utility bills and marriage records are already being added to Facebook's database, where they are easier to analyze. Facebook recently partnered with offline data companies, which all collect this kind of information. This move will allow even deeper insights into the behavior of the web users. 25 30 (3) - Sarah Downey, a lawyer and analyst with a privacy technology company, foresees insurers using the information gained by Facebook to help them identify risky customers, and perhaps charge them with higher fees. But there are potential benefits for users, too. Kosinski suggests that Facebook could end up as an online locker for your personal information, releasing your profiles at your command to help you with career planning. Downey says the research is the first solid example of the kinds of insights that can be made through Facebook. "This study is a great example of how the little things you do online show so much about you,” she says. "You might not remember liking things, " but Facebook remembers and (4) it all adds up.", * a 'like': フェイスブック上で個人の好みを表示する機能。 日本語版のフェイスブックでは「いいね!」 と表記される。 2-56 2-57 2-58 36

回答募集中 回答数: 0
TOEIC・英語 大学生・専門学校生・社会人

青くしてある文の文構造と訳し方を教えていただきたいです🙇‍♀️ また、mainstream America の語順に違和感を感じていて、(American mainstream とした方が正しくない?と思ってしまいます、、)それも解説いただきたいです。

Neil Hello. This is 6 Minute English from BBC Learning English. I'm Neil. Georgie And I'm Georgie. Neil If I told you I'd been for a walk to see Big Ben and Buckingham Palace, you'd know straight away I was in London. Georgie But what if my walk went past cafes selling mozzarella and ricotta where I smelled freshly made cannolis and focaccia... Where would I be then? Neil Focaccia and mozzarella... you'd be in Italy, right? Georgie Yes, Italy, or 'Little Italy' to be exact - the neighbourhood in some cities where Italian communities settled and made their home. Neil These Italian arrivals opened shops and cafes selling food to their own communities. Soon dishes like spaghetti and meatballs attracted the attention of local people, and gradually Italian food became famous around the world. In this programme, we'll be taking a walk through two Little Italys, one in Argentina, the other in New York, and, as usual, we'll be learning some useful new vocabulary as well. But before that, I have a question for you, Georgie. According to a recent YouGov poll, which Italian food is most popular with British diners? Is it: a) pizza? b) lasagne? or c) garlic bread? Georgie I think it must be pizza. Neil Okay, Georgie, I'll reveal the answer at the end of the programme. One country Italians moved to was Argentina. In 1898, Giuseppe Banchero arrived in the neighbourhood of La Boca, the Little Italy of Buenos Aires, where many Italian immigrants started restaurants. Here, Hugo Banchero, grandson of Giuseppe, tells his story to Veronica Smink, reporter for BBC World Service programme, The Food Chain: Hugo Banchero Well, my grandfather came from Italy, from Genoa, from Liguria. He was born in the centre of Genoa and arrived here in 1898 at the age of seven and a half, and this pizzeria where we are was founded on March 28, 1972. We have been here for 91 years. Veronica Smink So what culinary traditions did they bring with them? Hugo Banchero Well, our culinary tradition is pizza, and we incorporated the faina from Genoa, which is a pizza with chickpea flour... Georgie In 1898, Giuseppe founded his pizzeria - a restaurant selling pizza. When a business is founded, it's established someone starts it, or sets it up. Neil Giuseppe brought the culinary traditions from his home in Liguria in northern Italy, including regional pizzas like faina and fugazzetta. The adjective culinary describes anything connected with cooking. Georgie But probably the best-known Little Italy in the world is an area of Manhattan's Lower East side in New York. Ninety percent of Italian immigrants who arrived in the US at the turn of the century came through this neighbourhood. Neil De Palos, one of the original shops selling Italian food in Little Italy, has been serving customers for 113 years. Here, Lou De Palo, co-owner and great-grandson of the original owner, Salvino, explains more about his family history to BBC World Service programme, The Food Chain: Lou De Palo 1925... when my grandmother, Concetta, and my grandfather, Luigi, got married, they open their own shop... it's the shop we continue today being the fourth generation working alongside my sister, Maria, my brother, Sal, and our children, the fifth generation. Our business has expanded; expanded to present the full food culture of the 20 regions of Italy. Little Italy is the stepping stone of the Italian immigrant. This is where many of the Italians first came through Ellis Island, and then settled here, and then eventually moved into mainstream America throughout the rest of the country. Georgie Lou De Palo is the fourth generation of his family to run the shop, and his children will be the fifth. Phrases like fourth or fifth generation describe the children of people whose parents immigrated to a particular country.

未解決 回答数: 1
TOEIC・英語 大学生・専門学校生・社会人

lastに続くという意味はありますか?

A スクリプト W: How was the concert yesterday? M: Well, I enjoyed the performance a lot, but the concert only lasted an hour. W: Oh, that's kind of short. How much did you pay? M: About 10,000 yen. W: Wow, that's a lot! Do you think it was worth that much? M: No, not really. 女:昨日のコンサートどうだった? 男:えーと,僕は演奏はとても楽しんだけど コン サートはたった1時間しか続かなかった。 女:へえー,それは少し短いわね。 いくら払った の? 男:約10,000円。 女: わー, そんなにたくさん! あなたはそれだけ の価値があったと思う? 男: ないよ, それほど価値はなかったね。 質問 男性はコンサートについてどう考えていますか? 選択肢 ①それはもっと長く続くべきだった。 ②それは彼が予想した長さだった。 ③演奏はどちらかというと下手だった。 ④ 価格はより高くても良かった。 フグ 解説 正答率が21%で このテストでは一番難しい問題である。 ④ を選択した者が35% と一番多く、次 が③の28%である。 ①は3番目で,④が15%であった。 ダイアログ最後の not reallyの意味をとるのが 難しかったようである。 男性が, コンサートは1時間しか続かなかった, と発言していることに加えて 価格ほどの価値はなかったと言っているので,もっとコンサートが長ければ男性は満足したと考えるこ とができる。 そうすれば①が正解だと分かる。

未解決 回答数: 0
1/18